发明名称 |
DETERMINING SENSITIVITY OF CELLS TO B-RAF INHIBITOR TREATMENT BY DETECTING KRAS MUTATION AND RTK EXPRESSION LEVELS |
摘要 |
The present invention relates to prognostic methods for identifying tumors that are not susceptible to B-Raf inhibitor treatment by detecting mutations in a K-ras gene or protein or by detecting overexpression of RTKs and/or their ligands. Kits are also disclosed for carrying out the methods.
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申请公布号 |
US2012214828(A1) |
申请公布日期 |
2012.08.23 |
申请号 |
US201013392405 |
申请日期 |
2010.08.24 |
申请人 |
HATZIVASSILIOU GEORGIA;MALEK SHIVA |
发明人 |
HATZIVASSILIOU GEORGIA;MALEK SHIVA |
分类号 |
A61K31/517;A61P35/00;C12Q1/68;G01N33/574 |
主分类号 |
A61K31/517 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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