AMYLOID PROTEIN OLIGOMER BINDING APTAMER

摘要

An aptamer having a G-quartet structure and having the ability to bind to amyloid protein oligomer, the aptamer being at least one selected from the group consisting of the following polynucleotides: (1) a polynucleotide composed of the base sequence represented by any of SEQ ID NO: 1-18; (2) a polynucleotide composed of a base sequence which includes at least four groups of two or more consecutive guanosine nucleotides, and which results from one or a plurality of bases being deleted, substituted, or added in the base sequence represented by any of SEQ ID NO: 18; and (3) a polynucleotide which is a multimer that includes polynucleotide (1) or (2) as a structural unit.