DIAGNOSTIC KIT AND METHOD FOR EXAMINING A HUMAN PATIENT SAMPLE FOR THE PRESENCE OF ANTIBODIES SPECIFIC TO NEUROMYELITIS OPTICA

摘要

The invention relates to a diagnostic kit and method for examining a human patient sample for the presence of antibodies specific to neuromyelitis optica, wherein a starting substrate is incubated with human sample material and the incubated starting substrate is examined by means of indirect immunofluorescence in order to determine whether antibodies specific to neuromyelitis optica have bound at least partially to the starting substrate. The described solution is characterized in that a native substrate containing aquaporin 4 is used as the starting substrate and in that the antibodies specific to neuromyelitis optica that are at least partially bound to the starting substrate containing aquaporin 4 are reacted with components of the complement system and the reaction of the complement system is detected by way of an indicator reaction.