发明名称 SUBSTITUTED ISOQUINOLINONES AND QUINAZOLINONES.
摘要 <p>The invention relates to substituted nitrogen containing bicyclic heterocycles of the formula (I): wherein Z is CH<sub>2</sub> or N-R4 and X, R1, R2, R4, R6, R7 and n are as defined in the description. Such compounds are suitable for the treatment of a disorder or disease which is mediated by the activity of MDM2 and/or MDM4, or variants thereof.</p>
申请公布号 MX2012007336(A) 申请公布日期 2012.08.23
申请号 MX20120007336 申请日期 2010.12.21
申请人 NOVARTIS AG.* 发明人 KEIICHI MASUYA;PASCAL FURET;CAROLE PISSOT SOLDERMANN;FRANCOIS GESSIER;PHILIPP HOLZER;EDGAR JACOBY;STEFAN STUTZ;NICOLE BUSCHMANN;JOANNA HERGOVICH LISZTWAN;JOERG BERGHAUSEN;JOERG KALLEN;HAIXIA REN
分类号 A61P35/00;A61K31/495;C07D217/24;C07D401/04;C07D401/10;C07D401/12;C07D401/14;C07D405/04;C07D405/12;C07D405/14;C07D409/12;C07D413/10;C07D413/12;C07D413/14;C07D417/12 主分类号 A61P35/00
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