CHROMAN-SPIROCYCLIC PIPERIDINE AMIDES AS MODULATORS OF ION CHANNELS
摘要
The invention relates to chroman spirocyclic piperidine amide derivatives useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
申请公布号
CA2827311(A1)
申请公布日期
2012.08.23
申请号
CA20122827311
申请日期
2012.02.16
申请人
VERTEX PHARMACEUTICALS INCORPORATED
发明人
HADIDA-RUAH, SARA SABINA;MILLER, MARK THOMAS;KALLEL, EDWARD ADAM;BEAR, BRIAN RICHARD;ARUMUGAM, VIJAYALAKSMI;DENINNO, MICHAEL PAUL;ZHOU, JINGLAN;UY, JOHNNY;FRIEMAN, BRYAN A.