发明名称 |
HISTONE DEACETYLASE INHIBITORS AND METHODS OF USE THEREOF |
摘要 |
The present invention provides novel compounds for inhibiting histone deacetylases, and pharmaceutically acceptable salts and derivatives thereof. The present invention further provides methods for treating disorders regulated by histone deacetylase activity (e.g., proliferative diseases, cancer, inflammatory diseases, protozoal infections, hair loss, etc.) comprising administering a therapeutically effective amount of a compound of the invention to a subject in need thereof. The present invention also provides methods for preparing compounds of the invention. |
申请公布号 |
WO2012112447(A2) |
申请公布日期 |
2012.08.23 |
申请号 |
WO2012US24868 |
申请日期 |
2012.02.13 |
申请人 |
DANA-FARBER CANCER INSTITUTE, INC.;MAZITSCHEK, RALPH;BRADNER, JAMES, ELLIOTT;GRACHAN, MELISSA |
发明人 |
MAZITSCHEK, RALPH;BRADNER, JAMES, ELLIOTT;GRACHAN, MELISSA |
分类号 |
C07C69/76;A61K31/165;A61P29/00;C07C215/28 |
主分类号 |
C07C69/76 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|