发明名称 |
NOVEL AMINOPYRIDINE DERIVATIVES HAVING AURORA A SELECTIVE INHIBITORY ACTION |
摘要 |
<p>The present invention relates to a compound of Formula (I): wherein: n is 0 or 1; X is 0 or CH2; R1 is H or C1-2 alkyl; R2 is H or C1-3 alkyl; R3 and R4 are each independently H or C1-2 alkyl, where the alkyl may be substituted with one to three of the same or different substituents selected from R10; R5 is H or OCH3; R10 is F or Cl; or a pharmaceutically acceptable salt or ester thereof</p> |
申请公布号 |
EP2411012(A4) |
申请公布日期 |
2012.08.22 |
申请号 |
EP20100756585 |
申请日期 |
2010.03.15 |
申请人 |
MSD K.K.;VERTEX PHARMACEUTICALS INCORPORATED |
发明人 |
IWAMA, TOSHIHARU;KAWANISHI, NOBUHIKO;MORTIMORE, MICHAEL;OHKUBO, MITSURU;SUNAMI, TOMOKO |
分类号 |
A61K31/535;A61P35/00;C07D401/04;C07D471/04;C07D498/04 |
主分类号 |
A61K31/535 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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