<p>The present invention provides biologically active peptidomimetic macrocycles with improved properties, such as protease resistance, relative to their corresponding polypeptides. The invention additionally provides methods of preparing and using such macrocycles, for example in therapeutic applications.</p>
申请公布号
EP2488193(A1)
申请公布日期
2012.08.22
申请号
EP20100824134
申请日期
2010.10.14
申请人
AILERON THERAPEUTICS, INC.
发明人
NASH, HUW, M.;ANNIS, DAVID, ALLEN;GUERLAVAIS, VINCENT;LICKLIDER, LAWRENCE