发明名称 |
INCLUSION COMPLEX OF DEOXYPODOPHYLLOTOXIN OF CYCLODEXTRIN, PREPARATION METHOD, USE FOR TREAMENT OF CANCER THEREOF |
摘要 |
<p>Inclusion complex of deoxypodophyllotoxin of cyclodextrin, the preparation method and the use for the treatment of cancer thereof are disclosed. The inclusion complex consists of deoxypodophyllotoxin and beta-cyclodextrin derivative, wherein the molar ration of deoxypodophyllotoxin to beta-cyclodextrin derivative is 1:1-1:10. The beta-cyclodextrin derivative is sulfobutyl ether-beta-cyclodextrin or hydroxypropyl-beta-cyclodextrin.</p> |
申请公布号 |
EP2489351(A1) |
申请公布日期 |
2012.08.22 |
申请号 |
EP20100823054 |
申请日期 |
2010.10.01 |
申请人 |
CHINA PHARMACEUTICAL UNIVERSITY;LUO, HOUWEI;WU, BAOJIN;WU, CHANGXUAN |
发明人 |
LUO, HOUWEI;WU, BAOJIN;WU, CHANGXUAN;ZHU, XIONG |
分类号 |
A61K31/365;A61K47/40;A61K47/48;A61P35/00;A61P35/02 |
主分类号 |
A61K31/365 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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