发明名称 |
Methods for the formation of hydrogels using thiosulfonate compositions and uses thereof |
摘要 |
The present invention provides both crosslinked polymer compositions capable of forming hydrogels upon exposure to an aqueous environment and thiosulfonate hydrogel-forming components. The thiosulfonate hydrogel-forming components of the invention are preferably multi-arm thiosulfonate polymer derivatives that form a crosslinked polymer composition when exposed to a base without requiring the presence of a second cross-linking reagent, redox catalyst, or radiation. Methods for forming hydrogel compositions, as well as methods for using the hydrogels, are also provided. |
申请公布号 |
US8247598(B2) |
申请公布日期 |
2012.08.21 |
申请号 |
US201113325936 |
申请日期 |
2011.12.14 |
申请人 |
FANG ZHIHAO;BENTLEY MICHAEL D.;NEKTAR THERAPEUTICS |
发明人 |
FANG ZHIHAO;BENTLEY MICHAEL D. |
分类号 |
C09K5/06;A61K47/48;A61L24/00;A61L24/04;C07C381/04;C08G65/329;C08G65/334;C08J3/24;C08K3/00 |
主分类号 |
C09K5/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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