| 发明名称 |
ANTIVIRAL AGENT |
| 摘要 |
The present invention provides an integrase inhibitor. The inventors have have found the following compound of formula (I) possessing an integrase inhibitory activity. (see formula I) (wherein, R C and R D taken together with the neighboring carbon atoms form a ring which may be a condensed ring, Y is hydroxy, mercapto or amino; Z is O, S or NH ; R A is a group shown by (see formula II) (wherein, C ring is N-containing aromatic heterocycle or the like) |
| 申请公布号 |
CA2452769(C) |
申请公布日期 |
2012.08.21 |
| 申请号 |
CA20022452769 |
申请日期 |
2002.08.08 |
| 申请人 |
SHIONOGI & CO., LTD. |
发明人 |
KIYAMA, RYUICHI;KANDA, YASUHIKO;TADA, YUKIO;FUJISHITA, TOSHIO;KAWASUJI, TAKASHI;TAKECHI, SHOZO;FUJI, MASAHIRO |
| 分类号 |
C07D417/06;A61K31/00;A61K31/33;A61K31/352;A61K31/366;A61K31/4015;A61K31/4025;A61K31/4155;A61K31/4178;A61K31/4196;A61K31/422;A61K31/4245;A61K31/427;A61K31/433;A61K31/4427;A61K31/4433;A61K31/4439;A61K31/4709;A61K31/497;A61K31/501;A61K31/506;A61K31/53;A61P31/12;A61P31/18;A61P43/00;C07D207/38;C07D307/38;C07D307/46;C07D401/04;C07D403/04;C07D403/06;C07D405/04;C07D405/06;C07D407/06;C07D409/04;C07D409/06;C07D413/04;C07D413/06;C07D417/04 |
主分类号 |
C07D417/06 |
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