发明名称 |
Devices and methods for analyzing biomolecules and probes bound thereto |
摘要 |
Devices and methods for detecting the length of analytes and/or sequencing analytes are provided in which two or more electrical signals are obtained as an analyte traverses a nanopore or fluidic channel. Detection of the relative position of probes hybridized to a biomolecule and/or the length of the analyte (e.g., a biomolecule) rely on detection events to determine a distance associated with the biomolecule. Multiple signals may be obtained (e.g., as functions of time) corresponding to a plurality of detector volumes at known locations along a fluidic channel through which the biomolecule passes, and the distances may be determined from the multiple signals. |
申请公布号 |
US8246799(B2) |
申请公布日期 |
2012.08.21 |
申请号 |
US20100789817 |
申请日期 |
2010.05.28 |
申请人 |
OLIVER JOHN S.;IANAKIEV PETRE;NABSYS, INC. |
发明人 |
OLIVER JOHN S.;IANAKIEV PETRE |
分类号 |
G01N27/26 |
主分类号 |
G01N27/26 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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