| 摘要 |
Compounds of formula (I) are novel VR1 antagonists that are useful in treating pain, inflammatory thermal hyperalgesia, urinary incontinence and bladder overactivity, wherein X1, X2, X3, X4, X5, R5, R6, R7, R8a, R8b, R9, Z1, Z2 and L are as defined in the description. |
| 申请人 |
LEE CHIH-HUNG;BAYBURT EROL K.;DIDOMENICO, JR. STANLEY;DRIZIN IRENE;GOMTSYAN ARTHUR R.;KOENIG JOHN R.;PERNER RICHARD J.;SCHMIDT, JR. ROBERT G.;TURNER SEAN C.;WHITE TAMMIE K.;ZHENG GUO ZHU;ABBOTT LABORATORIES |
发明人 |
LEE CHIH-HUNG;BAYBURT EROL K.;DIDOMENICO, JR. STANLEY;DRIZIN IRENE;GOMTSYAN ARTHUR R.;KOENIG JOHN R.;PERNER RICHARD J.;SCHMIDT, JR. ROBERT G.;TURNER SEAN C.;WHITE TAMMIE K.;ZHENG GUO ZHU |
