发明名称 |
Methods of identifying and treating individuals exhibiting mutant kit protein |
摘要 |
The invention described herein relates to methods of identifying and treating individuals with protein tyrosine kinase associated disorders that have, or may, become resistant to treatment with a kinase inhibitor such as imatinib due to a gain-of-function mutation in KIT tyrosine kinase. |
申请公布号 |
US8247419(B2) |
申请公布日期 |
2012.08.21 |
申请号 |
US20060921781 |
申请日期 |
2006.06.09 |
申请人 |
LEE FRANCIS Y.;HEINRICH MICHAEL C.;BRISTOL-MYERS SQUIBB COMPANY;OREGON HEALTH AND SCIENCE UNIVERSITY;THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS |
发明人 |
LEE FRANCIS Y.;HEINRICH MICHAEL C. |
分类号 |
A61K31/497 |
主分类号 |
A61K31/497 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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