COMPOSITION CONTAINING MICRORNA FOR ENHANCING RADIATION SENSITIVITY

摘要

PURPOSE: A composition containing microRNA for enhancing radiosensitivity is provided to be used in an anticancer aid. CONSTITUTION: A pharmaceutical composition for enhancing radiation to cancer cells contains miRNA-302d of sequence number 1 or miRNA-196b of sequence number 2 as an active ingredient. An expression vector for intracellular transduction contains miRNA-302d or miRNA-196b. The expression vector is a linear DNA, plasmid DNA, or recombinant virus vector. The recombinant virus is lentivirus, retrovirus, adenovirus, adeno-associated virus, or herpes simplex. An anticancer aid contains the miRNA-302d or miRNA-196b as an active ingredient.