发明名称 |
(THIO)MORPHOLINE DERIVATIVES AS S1P MODULATORS |
摘要 |
The present disclosure relates to (thio)morpholine derivatives of the formula (I) or a pharmaceutically acceptable salt, a solvate or hydrate thereof; with the proviso that the derivative of formula (I) is not 2-(4-ethylphenyl)-4-morpholinoethanol or 4-[4-(2-hydroxyethyl)-2-morpholinyl]benzeneacetonitrile or a pharmaceutically acceptable salt, a solvate or hydrate thereof. The compounds of the invention have affinity to S1P receptors and may be used in the treatment, alleviation or prevention of S1P receptor mediated diseases and conditions. |
申请公布号 |
KR20120092103(A) |
申请公布日期 |
2012.08.20 |
申请号 |
KR20127008115 |
申请日期 |
2010.08.27 |
申请人 |
ABBOTT HEALTHCARE PRODUCTS B.V. |
发明人 |
IWEMA BAKKER WOUTER I.;COOLEN HEIN K.A.C.;MONS HARMEN;STOIT AXEL;RONKEN ERIC;VAN DER KAM ELIZABETH;FRANKENA JURJEN |
分类号 |
C07D265/30;A61K31/5375;A61P25/00;C07D413/12 |
主分类号 |
C07D265/30 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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