COMPOSITIONS FOR PREVENTING OR TREATING NEOPLASTIC DISORDERS COMPRISING MIRNA AS AN ACTIVE INGREDIENT

摘要

PURPOSE: A composition containing an agent which induces miR-494 or miR-494 overexpression is reduce the suppress growth of tumor cells. CONSTITUTION: A pharmaceutical composition for preventing or treating KIT(vkit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog)-mediated diseases or KIT-mediated diseases contains an agent which induces miRNA-494 or miR-494 overexpression. 20-100 serial nucleotides for preventing or treating KIT-mediated diseases or disorder contain an antisense oligonucleotide having a sequence which is complementary to 8th to 15th nucleotide sequences of sequence number 2.