PROCESS FOR THE DIFFERENTIATION OF ADULT STEM CELLS TO CHONDROCYTES OR OSTEOCYTES USING TAUROURSODEOXYCHOLIC ACID

摘要

PURPOSE: A method for differentiating adult stem cells to chodrocytes or osteocytes using tauroursodeoxycholic acid is provided to selectively suppress differentiation into adipocytes. CONSTITUTION: A method for differentiating adult stem cells to chodrocytes comprises a step of culturing adult stem cells in a medium for differentiation into chondrocytes containing tauroursodeoxycholic acid. The adult stem cells are adipose-derived stem cells. The medium is a DMEM medium containing tauroursodeoxycholic acid, TGF-1 beta, dexamethasone, ascorbic acid, insulin, transferring, and selenium.