发明名称 |
4-(Substituted Anilino)-Quinazoline Derivatives Useful as Tyrosine Kinase Inhibitors |
摘要 |
The present invention relates to 4-(substituted anilino)-quinazoline derivatives as tyrosine kinase inhibitors. Specifically, compounds of formula I, or pharmaceutically acceptable salts or solvates thereof are disclosed, in which each substitutent in formula I is defined in the description. Preparation method of the compounds of formula I, pharmaceutical compositions and pharmaceutical uses thereof are also disclosed. The compounds of formula I are effective tyrosine kinase inhibitors.
|
申请公布号 |
US2012208833(A1) |
申请公布日期 |
2012.08.16 |
申请号 |
US201013498547 |
申请日期 |
2010.09.20 |
申请人 |
WANG JINGYI;FAN CHUANWEN;ZHANG LONG;GUO ZHONGRU;LI YING;YANG SHAOBO;YAN SHOUSHENG;ZHU JIANRONG;YANG QINGMIN;ZHANG MINGHUI;QILU PHARMACEUTICAL CO., LTD. |
发明人 |
WANG JINGYI;FAN CHUANWEN;ZHANG LONG;GUO ZHONGRU;LI YING;YANG SHAOBO;YAN SHOUSHENG;ZHU JIANRONG;YANG QINGMIN;ZHANG MINGHUI |
分类号 |
A61K31/517;A61P35/00;A61P35/02;A61P35/04;C07D405/10 |
主分类号 |
A61K31/517 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|