ION MOBILITY SPECTROMETRY AND THE USE OF THE SEQUENTIAL ELIMINATION TECHNIQUE

摘要

The present disclosure describes a method of acquiring data and analyzing that data. The disclosure describes how useful information can be extracted from a collection of data; for example, how useful information can be extracted from data generated using IM-MS on a large macromolecular assembly. A method for analyzing IM-MS data is described which uses a multiscale approach providing a new paradigm for analyzing IM-MS data where simulations are guided to states consistent with the measured data.