| 发明名称 |
METHOD FOR PRODUCING ISOTHIAZOLE DERIVATIVE |
| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide intermediates and a method for producing the same in the production of isothiazole derivatives useful as a cancer therapeutic drug. <P>SOLUTION: In a method for producing isothiazole derivatives, compounds of formula (II) and their pharmaceutically acceptable salts are produced from specific amino group-containing raw material compounds. In the formula: R<SP POS="POST">1</SP>is a hydrogen atom or the like; R<SP POS="POST">2</SP>is an alkoxy group or the like; and R<SP POS="POST">3</SP>and R8 are each a hydrogen atom, an alkyl group or the like. <P>COPYRIGHT: (C)2012,JPO&INPIT |
| 申请公布号 |
JP2012153705(A) |
申请公布日期 |
2012.08.16 |
| 申请号 |
JP20120079463 |
申请日期 |
2012.03.30 |
| 申请人 |
PFIZER INC;OSI PHARMACEUTICALS INC |
发明人 |
DAMON DAVID B;JONES BRIAN P |
| 分类号 |
C07D275/02;A61K31/425;A61K31/427;A61K31/454;A61K31/496;A61P3/10;A61P27/02;A61P35/00;C07D417/12;C07D487/08 |
主分类号 |
C07D275/02 |
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