发明名称 GLUCAGON RECEPTOR MODULATOR
摘要 The present invention provides a compound of Formula (I) or a pharmaceutically acceptable salt thereof wherein R1, R2, R3, A1, A2, A3, A4, L, B1, B2, B3 and B4 are as defined herein. The compounds of Formula I have been found to act as glucagon antagonists or inverse agonists. Consequently, the compounds of Formula I and the pharmaceutical compositions thereof are useful for the treatment of diseases, disorders, or conditions mediated by glucagon.
申请公布号 WO2012107850(A1) 申请公布日期 2012.08.16
申请号 WO2012IB50349 申请日期 2012.01.25
申请人 PFIZER INC.;APNES, GARY ERIK;DIDIUK, MARY THERESA;FILIPSKI, KEVIN JAMES;GUZMAN-PEREZ, ANGEL;LEE, ESTHER CHENG YIN;PFEFFERKORN, JEFFREY ALLEN;STEVENS, BENJAMIN DAWSON;TU, MEIHUA MIKE 发明人 APNES, GARY ERIK;DIDIUK, MARY THERESA;FILIPSKI, KEVIN JAMES;GUZMAN-PEREZ, ANGEL;LEE, ESTHER CHENG YIN;PFEFFERKORN, JEFFREY ALLEN;STEVENS, BENJAMIN DAWSON;TU, MEIHUA MIKE
分类号 C07D207/34;C07D231/12;C07D231/14;C07D231/16;C07D231/18;C07D231/54;C07D231/56;C07D233/61;C07D233/64;C07D233/68;C07D233/70;C07D233/84;C07D249/06;C07D249/08;C07D261/08 主分类号 C07D207/34
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