发明名称 |
GLUCAGON RECEPTOR MODULATOR |
摘要 |
The present invention provides a compound of Formula (I) or a pharmaceutically acceptable salt thereof wherein R1, R2, R3, A1, A2, A3, A4, L, B1, B2, B3 and B4 are as defined herein. The compounds of Formula I have been found to act as glucagon antagonists or inverse agonists. Consequently, the compounds of Formula I and the pharmaceutical compositions thereof are useful for the treatment of diseases, disorders, or conditions mediated by glucagon. |
申请公布号 |
WO2012107850(A1) |
申请公布日期 |
2012.08.16 |
申请号 |
WO2012IB50349 |
申请日期 |
2012.01.25 |
申请人 |
PFIZER INC.;APNES, GARY ERIK;DIDIUK, MARY THERESA;FILIPSKI, KEVIN JAMES;GUZMAN-PEREZ, ANGEL;LEE, ESTHER CHENG YIN;PFEFFERKORN, JEFFREY ALLEN;STEVENS, BENJAMIN DAWSON;TU, MEIHUA MIKE |
发明人 |
APNES, GARY ERIK;DIDIUK, MARY THERESA;FILIPSKI, KEVIN JAMES;GUZMAN-PEREZ, ANGEL;LEE, ESTHER CHENG YIN;PFEFFERKORN, JEFFREY ALLEN;STEVENS, BENJAMIN DAWSON;TU, MEIHUA MIKE |
分类号 |
C07D207/34;C07D231/12;C07D231/14;C07D231/16;C07D231/18;C07D231/54;C07D231/56;C07D233/61;C07D233/64;C07D233/68;C07D233/70;C07D233/84;C07D249/06;C07D249/08;C07D261/08 |
主分类号 |
C07D207/34 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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