发明名称 |
MULTIPARTICULATE L-MENTHOL FORMULATIONS AND RELATED METHODS |
摘要 |
Enteric coated multiparticulate formulations that use L-menthol as an active ingredient are disclosed. In one embodiment, the multiparticulate formulation comprises a plurality of particulates having a reduced release under gastric conditions and an elevated release at neutral pH. The particulates comprise a core comprising L-menthol as an active ingredient. The L-menthol is supplied to the core as an at least 80% pure L-menthol material. An enteric coating is over the core. The enteric coating is effective to release at least about 80% of the L-menthol within about two hours of being placed in a substantially neutral pH environment. Other aspects of the invention include methods of making and methods of using the multiparticulate formulations.
|
申请公布号 |
US2012207842(A1) |
申请公布日期 |
2012.08.16 |
申请号 |
US201213367747 |
申请日期 |
2012.02.07 |
申请人 |
SHAH SYED M.;HASSAN DANIEL;HASSAN SARAH |
发明人 |
SHAH SYED M.;HASSAN DANIEL;HASSAN SARAH |
分类号 |
A61K31/045;A61K9/50;A61P1/00;B05D3/00;B05D5/00 |
主分类号 |
A61K31/045 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|