A method of analyzing genetic markers includes binding a set of probes to a segment of single stranded nucleic acids. The segment of single stranded nucleic acids includes a repeat region formed of at least two of a repeat unit. The repeat unit can include at least two nucleic acids. The set of probes includes a first probe complementary to the repeat unit. The method can further include directing the segment through a nanopore device and measuring a signal through the nanopore device. The signal can be indicative of the number of repeat units.
申请公布号
WO2012109483(A2)
申请公布日期
2012.08.16
申请号
WO2012US24544
申请日期
2012.02.09
申请人
LIFE TECHNOLOGIES CORPORATION;MERRIMAN, BARRY;MOLA, PAUL