发明名称 |
DIMENSIONAL ANALYSIS OF SACCHARIDE CONJUGATES WITH GPC & SEC MALS |
摘要 |
GPC (gel permeation chromatography) and size exclusion chromatography with detection by multi-angle light-scattering photometry (SEC-MALS) can be used to accurately measure molecular size and molar mass, respectively, of saccharide conjugates. The invention provides (a) a process for measuring the molecular size of a conjugated saccharide antigen within a sample, comprising a step of analysing the sample by GPC, and (b) a process for measuring the molar mass of a conjugated saccharide antigen within a sample, comprising a step of analysing the sample by SEC-MALS.
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申请公布号 |
US2012207781(A1) |
申请公布日期 |
2012.08.16 |
申请号 |
US201213454658 |
申请日期 |
2012.04.24 |
申请人 |
CAPANNOLI GIORGIO;CARINCI VALERIA;D'ASCENZI SANDRO;MAGAGNOLI CLAUDIA |
发明人 |
CAPANNOLI GIORGIO;CARINCI VALERIA;D'ASCENZI SANDRO;MAGAGNOLI CLAUDIA |
分类号 |
A61K39/095;A61K47/48;A61P31/04;C08B37/00;G01N21/49;G01N30/02 |
主分类号 |
A61K39/095 |
代理机构 |
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地址 |
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