| 发明名称 |
DISUBSTITUTED OCTAHYDROPYRROLO[3,4-c]PYRROLES AS OREXIN RECEPTOR MODULATORS |
| 摘要 |
Disubstituted octahydropyrrolo[3,4-c]pyrrole compounds are described, which are useful as orexin receptor modulators. Such compounds may be useful in pharmaceutical compositions and methods for the treatment of diseased states, disorders, and conditions mediated by orexin activity, such as insomnia. |
| 申请公布号 |
US2012208812(A1) |
申请公布日期 |
2012.08.16 |
| 申请号 |
US201013503231 |
申请日期 |
2010.10.21 |
| 申请人 |
CHAI WENYING;LETAVIC MICHAEL A.;LY KIEV S.;PIPPEL DANIEL J.;RUDOLPH DALE A.;SAPPEY KATHLEEN C.;SAVALL BRAD M.;SHAH CHANDRAVADAN R.;SHIREMAN BROCK T.;SOYODE-JOHNSON AKINOLA;STOCKING EMILY M.;SWANSON DEVIN M.;JANSSEN PHARMACEUTICA N.V. |
发明人 |
CHAI WENYING;LETAVIC MICHAEL A.;LY KIEV S.;PIPPEL DANIEL J.;RUDOLPH DALE A.;SAPPEY KATHLEEN C.;SAVALL BRAD M.;SHAH CHANDRAVADAN R.;SHIREMAN BROCK T.;SOYODE-JOHNSON AKINOLA;STOCKING EMILY M.;SWANSON DEVIN M. |
| 分类号 |
A61K31/5377;A61K31/423;A61K31/428;A61K31/444;A61K31/498;A61K31/506;A61K31/517;A61K31/53;A61P1/00;A61P1/04;A61P1/12;A61P3/00;A61P3/04;A61P3/06;A61P3/10;A61P9/00;A61P9/12;A61P15/00;A61P19/02;A61P25/00;A61P25/16;A61P25/18;A61P25/20;A61P25/22;A61P25/24;C07D487/04 |
主分类号 |
A61K31/5377 |
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