发明名称 |
Genetically encoded fluorescent coumarin amino acids |
摘要 |
The invention relates to orthogonal pairs of tRNAs and aminoacyl-tRNA synthetases that can incorporate the coumarin unnatural amino acid L-(7-hydroxycoumarin-4-yl) ethylglycine into proteins produced in eubacterial host cells such as . . The invention provides, for example but not limited to, novel orthogonal synthetases, methods for identifying and making the novel synthetases, methods for producing proteins containing the unnatural amino acid L-(7-hydroxycoumarin-4-yl) ethylglycine and related translation systems. |
申请公布号 |
AU2007267950(B2) |
申请公布日期 |
2012.08.16 |
申请号 |
AU20070267950 |
申请日期 |
2007.05.21 |
申请人 |
THE SCRIPPS RESEARCH INSTITUTE |
发明人 |
SCHULTZ, PETER G.;WANG, JIANGYUN;XIE, JIANMING |
分类号 |
C12N15/74 |
主分类号 |
C12N15/74 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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