发明名称 NITROGEN MONOXIDE PRODUCTION ENHANCER AND ANTITUMOR AGENT FROM MACROPHAGE, AND PHARMACEUTICAL COMPOSITION, FOOD, FEED AND COSMETIC INCLUDING THE SAME
摘要 <P>PROBLEM TO BE SOLVED: To provide a new physiologically active substance containing ascophyllan derived from Ascophyllum-nodosum which is highly safe with eaten experience as an active ingredient, and to provide a pharmaceutical composition, food, feed and a cosmetic including the same. <P>SOLUTION: There is provided an immunopotentiator containing as an active ingredient, ascophyllan which is a sulfated polysaccharide containing D-glucronic acid as a main component other than L-fucose and D-xylose, and which is extracted from Ascophyllum-nodosum which is one kind of brown algae, and having production inducing ability of induction type nitrogen monoxide synthetase (i-NOS) in macrophage, and antitumor activity to a solid cancer such as sarcoma, or the like. There is also provided a pharmaceutical composition containing the immunopotentiator and having immunopotent activity, an antitumor agent, and food, feed and a cosmetic containing these substances. <P>COPYRIGHT: (C)2012,JPO&INPIT
申请公布号 JP2012153612(A) 申请公布日期 2012.08.16
申请号 JP20110011458 申请日期 2011.01.21
申请人 NAGASAKI UNIV;HAYASHIKANE SANGYO KK 发明人 ODA TATSUYA;OKIMURA TAKASHI
分类号 A61K31/737;A23K1/16;A23L1/30;A61K8/73;A61P35/00;A61P43/00;A61Q19/00;C08B37/00 主分类号 A61K31/737
代理机构 代理人
主权项
地址