发明名称 |
PROCESS FOR DETERMINING THE SUITABILITY FOR DISTRIBUTION OF A BATCH OF A THIOPHENE-2-CARBOXAMIDE DERIVATIVE |
摘要 |
<p>The present invention relates to a process for determining the suitability for distribution of a batch of rivaroxaban or of a pharmaceutical composition thereof. In particular, it also relates to two impurities of rivaroxaban, to their use as reference markers to determine the purity of a sample of rivaroxaban or a composition thereof, to analytical methods for determining the purity of a sample of rivaroxaban or a composition thereof and to a process of preparing rivaroxaban or pharmaceutical compositions thereof which are free or substantially free of such impurities.</p> |
申请公布号 |
WO2012035057(A3) |
申请公布日期 |
2012.08.16 |
申请号 |
WO2011EP65925 |
申请日期 |
2011.09.14 |
申请人 |
MEDICHEM S.A.;MANGION, BERNARDINO;DURAN LOPEZ, ERNESTO |
发明人 |
MANGION, BERNARDINO;DURAN LOPEZ, ERNESTO |
分类号 |
C07D413/14 |
主分类号 |
C07D413/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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