发明名称 PROCESS FOR DETERMINING THE SUITABILITY FOR DISTRIBUTION OF A BATCH OF A THIOPHENE-2-CARBOXAMIDE DERIVATIVE
摘要 <p>The present invention relates to a process for determining the suitability for distribution of a batch of rivaroxaban or of a pharmaceutical composition thereof. In particular, it also relates to two impurities of rivaroxaban, to their use as reference markers to determine the purity of a sample of rivaroxaban or a composition thereof, to analytical methods for determining the purity of a sample of rivaroxaban or a composition thereof and to a process of preparing rivaroxaban or pharmaceutical compositions thereof which are free or substantially free of such impurities.</p>
申请公布号 WO2012035057(A3) 申请公布日期 2012.08.16
申请号 WO2011EP65925 申请日期 2011.09.14
申请人 MEDICHEM S.A.;MANGION, BERNARDINO;DURAN LOPEZ, ERNESTO 发明人 MANGION, BERNARDINO;DURAN LOPEZ, ERNESTO
分类号 C07D413/14 主分类号 C07D413/14
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