METHOD FOR DETECTING A PARKINSON'S DISEASE AND TEST SYSTEM

摘要

The present invention is directed to a method for detecting a Parkinson's disease (PD) comprising: a) providing an isolated sample which has been taken from an individual, b) determining the presence of at least one autoantibody against a myelin antigen and/of fragment(s) thereof in said isolated sample. The present invention is further directed to a method of monitoring the development and/or the course and/or the treatment of a Parkinson's disease (PD) comprising: a) providing a first sample isolated from an individual at a first time, b) determining the level of at least one autoantibody against a myelin antigen and/or fragment(s) thereof in said first sample, c) providing a second sample isolated from said individual at a second time, d) determining the level of said autoantibody in said second sample, e) comparing the determined level of said autoantibody in said second sample to the level of said autoantibody in said first sample. The present invention is further directed to a test system and an array for performing the method of the invention as well as the use at least one autoantibody against a myelin antigen and/or fragment(s) thereof for detecting a Parkinson's disease (PD).