发明名称 |
COMPOUND CONTAINING A NOVEL 4-ALKOXYPYRIMIDINE FORMATION AND MEDICINE CONTAINING SAME |
摘要 |
<p>Disclosed is novel compound and medicinal formulation containing same, possessing both angiotensin II receptor blocking and PPAR? activation effect, of use as a medicine for prevention and/or treatment of hypertension, heart disease, angina pectoris, cerebrovascular disorder, cerebral circulatory disturbances, post-ischemic peripheral circulatory damage, renal disease, arteriosclerosis, inflammatory disorder, type 2 diabetes, diabetic complications, insulin resistance syndrome, syndrome X, metabolic syndrome and hyperinsulinaemia. Further disclosed is the general formula I (where one or both of R1 and R2 represent a C1-6 alkyl group, R3 represents a C1-6 alkyl group which may contain one or more substituent groups selected from group A, or a C3-8 cycloalkyl group which may contain one or more substituent groups selected from group B.) which represents the compound, and salts thereof, solvates thereof, and medicinal compositions containing any of these.</p> |
申请公布号 |
WO2011105099(A8) |
申请公布日期 |
2012.08.16 |
申请号 |
WO2011JP01086 |
申请日期 |
2011.02.25 |
申请人 |
KOWA COMPANY, LTD.;MIURA, TORU;ONOGI, KAZUHIRO;TAGASHIRA, JUNYA;WATANABE, GEN;SEKIMOTO, RYOHEI;ISHIDA, RIE;AOKI, HITOMI;OHGIYA, TADAAKI |
发明人 |
MIURA, TORU;ONOGI, KAZUHIRO;TAGASHIRA, JUNYA;WATANABE, GEN;SEKIMOTO, RYOHEI;ISHIDA, RIE;AOKI, HITOMI;OHGIYA, TADAAKI |
分类号 |
C07D413/10;A61K31/506;A61K31/5377;A61P3/04;A61P3/10;A61P9/00;A61P9/10;A61P9/12;A61P13/12;A61P25/00;A61P27/02;A61P43/00;C07D413/14 |
主分类号 |
C07D413/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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