发明名称 |
COMPOSITIONS AND METHODS FOR MOBILIZING STEM CELLS |
摘要 |
<p>The present invention relates to the field of hematopoietic stem cells. More specifically, the present invention provides methods and composition useful for peripheral blood stem cell mobilization. In one embodiment, a method of treating an organ transplant recipient comprises administering to the recipient a low dose of Tacrolimus in an amount sufficient to mobilize stem cells to the peripheral blood of the recipient. In a specific embodiment, the low dose of Tacrolimus is in the range of about 0.05 mg/kg to about 0.5 mg/kg.</p> |
申请公布号 |
WO2012078746(A9) |
申请公布日期 |
2012.08.16 |
申请号 |
WO2011US63727 |
申请日期 |
2011.12.07 |
申请人 |
THE JOHNS HOPKINS UNIVERSITY;SUN, ZHAOLI;OKABAYASHI, TAKEHIRO |
发明人 |
SUN, ZHAOLI;OKABAYASHI, TAKEHIRO |
分类号 |
A61K31/436;A61K31/44;A61P1/16;A61P9/00;A61P35/00 |
主分类号 |
A61K31/436 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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