发明名称 |
METHOD FOR DETECTING AND DETERMINING INTRAHEPATIC CHOLANGIOCARCINOMA |
摘要 |
Disclosed are a method for early, sensitively and reliably detecting and distinguishing intrahepatic cholangiocarcinoma in a malignant tumor occurring primarily in the liver in a simple way, and a kit therefor. In the method, a glycan biomarker consisting of a lectin WFA (Wisteria floribunda Agglutinin)-binding glycoprotein derived from intrahepatic cholangiocarcinoma is used as a cancer marker to detect intrahepatic cholangiocarcinoma by detecting the cancer marker in a test specimen. The method for detecting intrahepatic cholangiocarcinoma can clearly differentiate intrahepatic cholangiocarcinoma from hepatocellular carcinoma and enables early detection and determination with a performance clinically acceptable in terms of applicability, sensitivity and precision. |
申请公布号 |
EP2405269(A4) |
申请公布日期 |
2012.08.15 |
申请号 |
EP20100748464 |
申请日期 |
2010.02.23 |
申请人 |
NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCEAND TECHNOLOGY;UNIVERSITY OF TSUKUBA |
发明人 |
KUNO, ATSUSHI;HIRABAYASHI, JUN;MATSUDA, ATSUSHI;NARIMATSU, HISASHI;IKEHARA, YUZURU;SHODA, JUNICHI;KAWAMOTO, TORU |
分类号 |
G01N33/574;G01N21/64;G01N37/00 |
主分类号 |
G01N33/574 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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