发明名称 |
ANTI-VLA-4 RELATED ASSAYS |
摘要 |
Methods and apparatus for assaying the level of analytes in a sample, related to VLA-4, are disclosed. A method of decreasing the level of an anti-integrin antibody in a subject is described including a) contacting a biological sample from a subject with a detectable capture agent associated with a substrate, wherein the capture agent can bind an anti-integrin antibody in the sample; b) detecting binding of the capture agent with the level of the anti-integrin antibody; and c) treating the subject with plasma exchange until the level of the anti-integrin antibody in the sample reaches a predetermined level. |
申请公布号 |
EP2485762(A1) |
申请公布日期 |
2012.08.15 |
申请号 |
EP20100822820 |
申请日期 |
2010.10.11 |
申请人 |
BIOGEN IDEC MA INC. |
发明人 |
PLAVINA, TATIANA;HOCHMAN, PAULA, S.;LERNER, MICHAELA |
分类号 |
A61K39/395 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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