发明名称 |
USE OF TOLL-LIKE RECEPTOR AND AGONIST FOR TREATING CANCER |
摘要 |
<p>The present invention is directed to methods and agents used for treating cancer or infectious diseases by providing toll-like receptors such as toll-like receptor 5 (TLR-5) in combination with providing a toll-like receptor agonists such as flagellin resulting in a cis and intrans effect that recruits cells involved in both the innate (cis effect) and adaptive (trans effect) immune response to specifically kill cancer cells and cells infected with a pathogen via the NF-&kgr;B apoptosis pathway.</p> |
申请公布号 |
EP2486134(A1) |
申请公布日期 |
2012.08.15 |
申请号 |
EP20100822611 |
申请日期 |
2010.10.06 |
申请人 |
PANACELA LABS, INC.;ROSWELL PARK CANCER INSTITUTE |
发明人 |
GUDKOV, ANDREI, V. |
分类号 |
C12N15/63;A61K38/16;A61K38/17;A61P31/04;A61P35/00 |
主分类号 |
C12N15/63 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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