发明名称 COMPOSITIONS AND METHODS FOR INHIBITING CELLULAR ADHESION OR DIRECTING DIAGNOSTIC OR THERAPEUTIC AGENTS TO RGD BINDING SITES.
摘要 Compounds comprising R-G-Cysteic Acid (i.e., R-G-NH-CH(CH<sub>2</sub>- SO<sub>3</sub>H)COOH or Arg-Gly-NH-CH(CH<sub>2</sub>-SO<sub>3</sub>H)COOH) and derivatives thereof, including pharmaceutically acceptable salts, hydrates, stereoisomers, multimers, cyclic forms, linear forms, drug-conjugates, pro-drugs and their derivatives. Also disclosed are methods for making and using such compounds including methods for inhibiting cellular adhesion to RGD binding sites or delivering other diagnostic or therapeutic agents to RGD binding sites in human or animal subjects.
申请公布号 MX2012005222(A) 申请公布日期 2012.08.15
申请号 MX20120005222 申请日期 2010.11.10
申请人 ALLEGRO PHARMACEUTICALS, INC.* 发明人 JOHN PARK;MICHAEL JOHN MACKEL
分类号 A61K51/06;A61K51/08;A61P3/00;A61P29/00;A61P35/00 主分类号 A61K51/06
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