发明名称 Cell penetrating peptides for intracellular delivery of molecules
摘要 The present invention concerns cell-penetrating peptides which comprise an amino acid sequence consisting of GLX9RALX9RX1LX2RSLX9X3X4X5X6X7X8 (SEQ ID No: 1), wherein X1 is A, L or G, X2 is W or none, X3 is R or K, X4 is K, L or S, X5 is L or K, X6 is R or W, X7 is K or S, and X8 is A, V or Q, and X9 is W, F or Y. These CPPs can be used as vectors for delivering nucleic acids and/or proteins and/or peptides to cells, in vitro or in vivo.
申请公布号 US8242081(B2) 申请公布日期 2012.08.14
申请号 US20060096378 申请日期 2006.12.05
申请人 DIVITA GILLES;HEITZ FREDERIC;MORRIS MAY CATHERINE;ALDRIAN-HERRADA GUDRUN;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE;AFFYMETRIX, INC. 发明人 DIVITA GILLES;HEITZ FREDERIC;MORRIS MAY CATHERINE;ALDRIAN-HERRADA GUDRUN
分类号 A61K38/10;A61K47/00;A61K48/00;C12N15/11;C12N15/113 主分类号 A61K38/10
代理机构 代理人
主权项
地址