发明名称 |
Use of cis-epoxyeicosatrienoic acids and inhibitors of soluble epoxide hydrolase to reduce cardiomyopathy |
摘要 |
The invention provides methods for inhibiting cardiomyopathy and for inhibiting cardiac arrhythmia, by administering to an individual in need thereof a cis-epoxyeicosantrienoic acid, an inhibitor of soluble epoxide hydrolase (sEH), or both. In some embodiments, the method comprises administering to the individual a nucleic acid encoding an inhibitor of sEH. Cardiomyopathies treatable by the methods of the invention include cardiac hypertrophy and dilated cardiomyopathy. |
申请公布号 |
US8242170(B2) |
申请公布日期 |
2012.08.14 |
申请号 |
US20060921676 |
申请日期 |
2006.06.06 |
申请人 |
CHIAMVIMONVAT NIPAVAN;HAMMOCK BRUCE D.;THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
CHIAMVIMONVAT NIPAVAN;HAMMOCK BRUCE D. |
分类号 |
A01N43/24;A61F2/06;A61M31/00;C12N15/113 |
主分类号 |
A01N43/24 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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