| 发明名称 |
Method and compounds for inhibition of cell death |
| 摘要 |
The invention is directed to methods and compositions for inhibiting caspase-independent apoptosis. In particular, methods and compositions for inhibiting Omi/HtrA2 activity, as well as method for identifying other inhibitors of Omi/HtrA2. Also disclosed are Omi/HtrA2 specific substrates and methods for identifying other substrates of Omi/HtrA2. |
| 申请公布号 |
US8242122(B2) |
申请公布日期 |
2012.08.14 |
| 申请号 |
US20100751036 |
申请日期 |
2010.03.31 |
| 申请人 |
ZERVOS ANTONIS S.;UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. |
发明人 |
ZERVOS ANTONIS S. |
| 分类号 |
A01N43/54;A61K31/00;A61K31/515;C07D239/00;C07D239/02;C07D239/42;C07D239/70;C07D401/04;C07D471/00 |
主分类号 |
A01N43/54 |
| 代理机构 |
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