| 摘要 |
FIELD: medicine. ^ SUBSTANCE: invention relates to medicine, namely to oncology and deals with method of treatment in case of urinary bladder cancer. Combined treatment with application of neoadjuvant system polychemical therapy by the following scheme: 1 day -5-fluoruracyl, 2 day - cyclophosphane+vinblastine, 14 day - methotrexate, 15 day - doxorubicin, 16 day -cisplatin, and adjuvant intrabladder chemical therapy with preparation doxorubicin during 2 years, on the first day after operation doxorubicin 40 mg is instilled, then 4 instillations of doxorubicin in dose 40 mg with 7 day interval, then doxorubicin 40 mg is instilled with 30 day interval during 11 months, after that during the second year instillations of doxorubicin in dose 20 mg are performed after 1 month. ^ EFFECT: invention ensures improvement of results of organ-preserving treatment by reduction of number of urinary bladder cancer recurrences. ^ 1 ex |
