ANTIBODIES NEUTRALISING GRANULOCYTIC MACROPHAGEAL COLONY-STIMULATING HUMAN FACTOR

摘要

FIELD: medicine. ^ SUBSTANCE: invention represents a human monoclonal antibody or its fragment which specifically binds with primate GM-CSF and neutralise it. There are also presented a polynucleotide molecule, a pharmaceutical composition, application of the monoclonal antibody. ^ EFFECT: invention may be used for neutralising higher or undesired activity of primate GM-CSF. ^ 22 cl, 34 dwg, 5 tbl, 11 ex