OPTICALLY ACTIVE CYCLIC ALCOHOL COMPOUND AND METHOD FOR PRODUCING SAME

摘要

The present invention relates to a method for preparing an optically active cyclic alcohol compound represented by general formula [I]:
[wherein R represents a hydrogen atom or a protecting group for amino group, and * represents an asymmetric carbon atom.]
which comprises a step of subjecting a cyclic ketone compound represented by general formula [II]:
[wherein R has the same meaning as defined above.] to asymmetric reduction (A) in the presence of an optically active oxazaborolidine compound and a boron hydride compound, or (B) in the presence of an asymmetric transition metal complex obtained from a transition metal compound and an asymmetric ligand and a hydrogen donor, and relates to said compound.