发明名称 COMBINAISON DE BIOMARQUEURS POUR LE PRONOSTIC D'UNE REPONSE OU NON-REPONSE A UN TRAITEMENT ANTI-VHC
摘要 The application concerns means for predicting whether a subject infected with one or more HCVs has a high probability of responding to an anti-HCV treatment which will comprise the administration of interferon and of ribavirin or whether, in contrast, that subject has a high probability of not responding to that anti-HCV treatment. The means of the invention in particular involve assaying the levels of expression of selected genes, said selected genes being: at least one gene from among MBL2, LGALS3BP and IL8, and at least one gene from among G1P2, CCL21 and CXCL10, and optionally, at least one gene from among AFP, CRP, CXCL11, CXCL6, CXCL9, FGF7, MDK, MMP2, SFN, TGFB2 and VEGFD.
申请公布号 FR2971258(A1) 申请公布日期 2012.08.10
申请号 FR20110051031 申请日期 2011.02.09
申请人 BIO RAD PASTEUR;ARIANA PHARMACEUTICALS;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE;ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE 发明人 BIECHE IVAN;WATELET BENEDICTE;ASSELAH TARIK;BATXELLI ISABELLE, CATHERINE;MATHIEU EVE LAURE;JULLIAN NATHALIE;VIDAUD MICHEL;MARCELLIN PATRICK;AFSHAR MOHAMMAD
分类号 C12Q1/68;G01N33/576;G01N33/68;G06F19/20 主分类号 C12Q1/68
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