| 发明名称 |
NEW COMPOUNDS ACTING AS ERK INACTIVATORS |
| 摘要 |
FIELD: chemistry. ^ SUBSTANCE: invention refers to new indazole derivants with the formula (1.0) or to their pharmaceutically acceptable salts and isomerides that act as inactivators in relation to ERK2. In formula (1.0): meanings of the chemical groups Q, R1, R2 are given in the invention formula. The invention also refers to the pharmaceutical composition containing the mentioned compounds and to application of the compounds with the formula (1.0) for production of crude drugs used in malignant growth treatment. ^ EFFECT: application of the compounds for production of crude drugs used in malignant growth treatment. ^ 65 cl, 611 ex, 27 tbl |
| 申请公布号 |
RU2442778(C9) |
申请公布日期 |
2012.08.10 |
| 申请号 |
RU20080128119 |
申请日期 |
2006.12.11 |
| 申请人 |
SHERING KORPOREJSHN |
发明人 |
KUPER ALAN;DENG JONGKI;SHIPPS DZHERAL'D V. ML.;SHIKH NENG-JANG;ZHU KH'JU;SAN ROBERT;KELLI DZHOZEF;DOLL RONAL'D;NAN JANG;VANG TONG;DESAI JAGDISH;VANG DZHEJMS;DONG JUKHAO;MEHDISON VINSENT S.;KSIAO LI;KHRUZA ALAN;SIDDIKI M. ARSHAD;SAMATAR AKHMED;PALIVAL SUNIL;TSUI KHON-CHUNG;CHELEBI AZIM A.;VU JIDZHI;BOGA SOBKHANA BABU |
| 分类号 |
A61K31/427;A61K31/428;A61K31/496;A61K31/506;A61P35/00;C07D231/56;C07D403/12;C07D403/14;C07D409/12;C07D413/12;C07D417/12;C07D417/14 |
主分类号 |
A61K31/427 |
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