| 摘要 |
FIELD: medicine. ^ SUBSTANCE: group of inventions refers to medicine, namely a catheter, particularly a catheter for collection of a number of samples inside a blood vessel along its length, and related methods, particularly a method for creating a data profile for one or more biomarkers recovered from a blood vessel wall, a method for profiling a length of the blood vessel for determination of the pathological or physiological state of the blood vessel wall, and a method for blood sampling in vivo from the blood vessel. A catheter comprises an elongated central body, at least one collection portion limited along the elongated central body for sample collection in the central portion of the blood vessel, and at least one mixer presented radially outside the elongated central body. Said body is introduced in the blood vessel and arranged along it. At least one mixer extends around said body circumferentially substantially in all radial directions. The mixer is presented to serve as an blood flow obstruction along the blood vessel to create a blood flow from a layer bordering the blood vessel wall along the whole periphery of the blood vessel in said body so that to enable said at least one collection portion collecting samples from the bordering layer. ^ EFFECT: invention provides improved better result consistency and closer correlation of the actual positions of biomarker sources and the positions in which such biomarkers are initially collected. ^ 23 cl, 25 dwg, 1 tbl |
