PHARMACEUTICAL FORMULATIONS INCLUDING AN AMINE COMPOUND
摘要
<p>The present invention relates to solid, semisolid, or liquid formulations comprising amine compounds that prevent or reduce formic acid and/or formyl species generation in the dosage form during the manufacturing process and/or during shelf -life storage. The formulations of the present invention prevent or reduce formation of N- formyl impurities (and gelatin crosslinking) during the manufacturing process and/or during shelf -life storage.</p>
申请公布号
WO2012106303(A1)
申请公布日期
2012.08.09
申请号
WO2012US23262
申请日期
2012.01.31
申请人
BRISTOL-MYERS SQUIBB COMPANY;ASTRAZENECA UK LIMITED;NARANG, AJIT;RAO, VENKATRAMANA, M.;DESAI, DIVYAKANT, S.
发明人
NARANG, AJIT;RAO, VENKATRAMANA, M.;DESAI, DIVYAKANT, S.