发明名称 |
Compositions and methods of improving the tolerability of daunorubicin when given as orotate salt |
摘要 |
This invention is in the field of anthracycline family of drugs. More particularly, it concerns converting daunorubicin hydrochloride to an orotate salt and providing methods of improving the tolerability of daunorubicin in animals by reducing the adverse effects and toxicity in noncancerous tissues. Daunorubicin orotate provides a safer treatment for specific types of leukemias and neuroblastomas in adults and in pediatric patients.
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申请公布号 |
US2012202761(A1) |
申请公布日期 |
2012.08.09 |
申请号 |
US201213385638 |
申请日期 |
2012.02.27 |
申请人 |
KARMALI RASHIDA A.;SAVVIPHARM INC |
发明人 |
KARMALI RASHIDA A. |
分类号 |
A61K31/704;A61P35/00;C07H15/24 |
主分类号 |
A61K31/704 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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