摘要 |
<P>PROBLEM TO BE SOLVED: To provide a process for the preparation of 17-esters of 9 α,21-dihalo-pregnane-11β,17α-diol-20-ones. <P>SOLUTION: The process for the preparation of related 17-esters, represented by the following formula, includes reacting 17α-hydroxy of 9α,21-dihalo-pregnane-11β,17α-diol-20-ones with 2-furoyl chloride. The compound is useful as an anti-inflammatory. <P>COPYRIGHT: (C)2012,JPO&INPIT |