| 摘要 |
<p>The invention relates to a material or biomaterial comprising silicic acid condensates having a low degree of cross-linking as well as to methods for the production of said material/biomaterial. In a disclosed method for producing poorly cross-linked silicic acid structures, a sol is produced while further condensation is prevented once a certain degree of cross-linking of the silicic acid has been reached. Preferably, structures having a size of 0.5 to 1000 nm are produced, e.g. polyhedral structures or aggregates thereof. Further condensation can be prevented by mixing the silicic acid with a polymer. In one embodiment, the material comprises nanostructured, poorly cross-linked silicon dioxide (SiO2) embedded in a polymer matrix. The material can be used in the medical field for therapeutic purposes and can enter in direct contact with biological tissue of the body. Said material interacts chemically, physically, and biologically with the respective biological systems. It is degradable and can supply the silicic acid needed for metabolism. Moreover, the material can have a supporting or shielding effect and can be provided in the form of a granulate, microparticles, fiber and woven or nonwoven fabric made therefrom, or as a layer on implants or wound dressings. The material can be used as a medical product or as a food supplement.</p> |
