发明名称 |
INHIBITORS OF ERK FOR DEVELOPMENTAL DISORDERS OF NEURONAL CONNECTIVITY |
摘要 |
<p>A method of treating a subject at risk of or suspected of having Fragile X syndrome or autism spectrum disorder associated with abnormalities of ERK includes administering to the subject a therapeutically effective amount of at least one ERK inhibiting compound that prevents abnormalities in neuronal connectivity, a prodrug thereof that is metabolisable to form the compound, or a pharmaceutically acceptable salt thereof.</p> |
申请公布号 |
WO2012019113(A3) |
申请公布日期 |
2012.08.09 |
申请号 |
WO2011US46773 |
申请日期 |
2011.08.05 |
申请人 |
CASE WESTERN RESERVE UNIVERSITY;SMITH, MARK, A.;SNAPE, MICHAEL |
发明人 |
SMITH, MARK, A.;SNAPE, MICHAEL |
分类号 |
A61K31/353;A61K31/4184;A61K31/439;A61P25/00;A61P43/00 |
主分类号 |
A61K31/353 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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